Evolution of the Craniofacial Features in Surface fish and Cavefish

Start Date

7-8-2026 10:45 AM

End Date

7-8-2026 11:00 AM

Location

ALT 205

Abstract

The craniofacial features of the Astyanax Mexicanus species have evolved overtime as new caves are discovered and new specimens are collected. Exact genes that contribute to the alterations of craniofacial features of both fish are still unknown. Being that skull and body size are some of the main differences between cavefish and surface fish, analyzing these elements will help us understand the evolution of craniofacial features-ultimately mapping genetic development. Using high-definition micro-computed technology and a 3D slicer software, we have developed three-dimensional, measurable skeletal scans. Quantitative trait analysis has helped us to connect phenotypic traits with multiple genes, assisting us in gathering evolutionary information on Astyanax Mexicanus. Use of the quantitative trait locus (QTL) data has guided us to specific regions of genomes, with those regions providing multiple genes. Future experiments will include comparing these various genes between cavefish and surface fish, observing their mutations, especially with craniofacial features and phenotypic evolution. Current efforts using transcriptomic analysis will allow cross referencing of gene expression of both cavefish and surface fish, comparing the two variants.

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Aug 7th, 10:45 AM Aug 7th, 11:00 AM

Evolution of the Craniofacial Features in Surface fish and Cavefish

ALT 205

The craniofacial features of the Astyanax Mexicanus species have evolved overtime as new caves are discovered and new specimens are collected. Exact genes that contribute to the alterations of craniofacial features of both fish are still unknown. Being that skull and body size are some of the main differences between cavefish and surface fish, analyzing these elements will help us understand the evolution of craniofacial features-ultimately mapping genetic development. Using high-definition micro-computed technology and a 3D slicer software, we have developed three-dimensional, measurable skeletal scans. Quantitative trait analysis has helped us to connect phenotypic traits with multiple genes, assisting us in gathering evolutionary information on Astyanax Mexicanus. Use of the quantitative trait locus (QTL) data has guided us to specific regions of genomes, with those regions providing multiple genes. Future experiments will include comparing these various genes between cavefish and surface fish, observing their mutations, especially with craniofacial features and phenotypic evolution. Current efforts using transcriptomic analysis will allow cross referencing of gene expression of both cavefish and surface fish, comparing the two variants.