Flow Injection/sequential Injection Chromatography: A Review of Recent Developments in Low Pressure with High Performance Chemical Separation

Supaporn Kradtrap-Hartwell, Xavier University - Cincinnati
A. Kehling
J. Lapanantnoppakhun
K. Grudpan


This review focuses on the developments of the various parts of instrumentation and the operation of low to medium pressure flow injection and sequential injection chromatography (FIC and SIC) systems. The report and discussion include solution delivery system, separation column, flow cell and detector, mobile phase management, and online sample pretreatment. Applications of FIC and SIC and their differences as compared to HPLC are also presented.